Selasa, 27 Juni 2017

Gore

Understanding
Gore or polycythaemia is an increase in the number of blood cells (red blood cells, white blood cells, blood chips) above the normal amount. The disease has many variations. Some are conditions of hypertension, obesity or obesity, stress, hypoxia (lack of oxygen levels in cells), or due to gene mutations in stem cells in the bone marrow. If there is a gene mutation, it is called polycythemia vera.

Polycythaemia can increase the risk of occlusion of blood vessels (arteries or veins). This facilitates the occurrence of complications of some types of stroke or heart attack.


Diagnosis
Determination of the diagnosis of thick blood or polycythemia can be done through a blood test. On the examination of the blood will be examined to know some things, such as:

  • Increase in the number of red blood cells. Sometimes it can also be accompanied by increased platelets and white blood cells.
  • Increased hematocrit. Hematocrit is the percentage of red blood cells in the blood volume of hemoglobin enhancement.
  • Increased hemoglobin. It is an iron-rich protein that carries oxygen in red blood cells.
  • Erythropoietin. This is a hormone that stimulates the bone marrow to produce new red blood cells.
  • Bone marrow aspiration or biopsy. If the laboratory examination of blood is suspected polycythemia. Bone marrow samples will be taken and analyzed for histological examination.

Symptoms
Most people with thick blood or polycythemia do not feel any significant symptoms. However, in some cases, there are symptoms of polycythemia that have been reported. For example:

  • Itching, especially after bathing with warm water
  • Headache or dizziness
  • Weak
  • Excessive sweating
  • Shortness of breath, especially when lying down
  • Swelling accompanied by pain in one joint, often the joint of the big toe
  • Numbness or numbness, tingling, weakness in the hands, arms, legs, or legs
  • Bloating or of obstruction in the upper left abdomen due to enlargement of the spleen 

Treatment
Current polycythaemia therapies aim to reduce symptoms and prolong the patient's life possibilities. Unfortunately until now there has been no therapy that can cure patients one hundred percent. However, polycythemia patients still require treatment to improve their quality of life.

Treatment will be tailored to the cause of the polycythaemia. If the cause of polycythaemia is unknown, then what is required is a regular monitor. The main treatment is aimed at preventing the formation of blockages and to reduce the itchy complaints that arise. The trick is the use of drugs and therapy.

Drugs used to function to suppress the production of blood cells in the bone marrow. Treatment of polycythaemia is generally done by reducing or removing blood from the body until the amount of hematocrit is within normal limits. 


CauseThe cause of thick blood or polycythaemia is divided into two groups, namely primary and secondary causes.
The primary cause. Bone marrow produces too many red blood cells due to genetic mutations. This is referred to as polycythemia vera. This condition is rare, but can be found in middle age and parents.
Secondary causes. Bone marrow produces too many red blood cells due to lack of oxygen levels in the body. When oxygen levels decrease, the bone marrow responds to the need for additional oxygen by producing more red blood cells.
Oxygen deficiency can be caused by chronic lung disease such as Chronic Obstructive Pulmonary Disease (COPD), kidney disease, Cushing's syndrome, hemangioblastoma, and someone who is at altitude (eg mountains).
There is another form of polycythemia that is relative polycythemia. The cause is quite diverse, including too much alcohol, obesity, hypertension, stress, and dehydration (lack of fluids). Generally this type of polycythemia condition is temporary and can return to normal as long as the cause is overcome.
 


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